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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: J Vet Pharmacol Ther. 2010 Feb;33(1):15–21. doi: 10.1111/j.1365-2885.2009.01098.x

Table 1.

Acetaminophen pharmacokinetic parameters after a single oral administration to 6 healthy Greyhound dogs.

Geometric Mean Min Median Max
Dose mg/kg 10.46 8.28 11.21 11.86
AUCextrap % 2.04 1.68 1.88 2.04
AUC0-inf hr* μg /mL 13.78 11.11 13.49 16.25
AUMC0-inf hr*hr* μg/mL 27.12 20.03 27.29 37.38
Cl/F mL/min/kg 12.65 10.55 12.11 17.70
CMAX μg/mL 6.74 4.48 6.80 8.88
T ½ λz hr 0.96 0.76 0.99 1.13
λz /hr 0.73 0.61 0.70 0.92
MRT hr 1.97 1.69 1.85 2.70
TMAX hr 0.85 0.50 0.63 2.00
Vz/F L/kg 1.05 0.86 1.04 1.57