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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: J Comp Neurol. 2010 Apr 15;518(8):1370–1390. doi: 10.1002/cne.22282

Figure 7.

Figure 7

BLBP expression is chronically upregulated in spared white matter, while nestin expression only transiently increases. (A–D) Confocal images of GFAP (green), BLBP (red), and nestin (blue) in naïve tissue (A–A''') and 1.0 mm caudal from the lesion epicenter at 3 (B–B'''), 7 (C–C''') and 49 (D–D''') DPI. Inset depicts region shown in confocal images. (E–F) Quantification of the proportion of merged staining area represented by GFAP, BLBP, and nestin immunoreactivity over time both rostral (E) and caudal (F) to the injury epicenter. The dotted line in each graph depicts the proportion of merged staining colocalized with each of the markers in naïve tissue specimens. Scale = 20 μm. **p < 0.01 (nestin caudal 3 and 7 vs. 49 DPI), ***p < 0.001 (BLBP rostral 3 vs. 7 and 49 DPI; BLBP caudal 3 vs. 7 and 49 DPI; BLBP caudal 7 vs. 49 DPI).