Skip to main content
. Author manuscript; available in PMC: 2010 May 11.
Published in final edited form as: Inhal Toxicol. 2009 Feb;21(3):223–233. doi: 10.1080/08958370802492407

TABLE 4.

Cardiac repolarization parameters, exposures to 10 and 25 µg/m3 with exercise, difference from baseline

ECG parameter/
exposure		 During
exposure		 Hours after exposure
 ANOVA
0 3.5 15 21
QTc (msec)
    Air 37 ± 10 19 ± 9 21 ± 7 10 ± 5 23 ± 9 UFP:
    10 µg/m3 −53 ± 5 6 ± 5 −17 ± 8 −3 ± 10 1 ± 5 p <0.001
    25 µg/m3 27 ± 11 0.1 ± 4 5 ± 3 −5 ± 9 7 ± 4
T- wave amplitude (µV)
    Air −75 ± 42 74 ± 26 −41 ± 36 −42 ± 22 6 ± 22 UFP:
    10 µg/m3 −41 ± 38 106 ± 24 3 ± 25 −13 ± 22 38 ± 18 p = 0.026
    25 µg/m3 −66 ± 40 86 ± 34 −9 ± 21 −18 ± 26 28 ± 18
PCA
    Air −1 ± 2 −2 ± 2 1 ± 2 −1 ± 0.8 −1 ± 1 NS
    10 µg/m3 −2 ± 1 −3 ± 1 −0.1 ± 0.8 1 ± 2 −0.3 ± 0.8
    25 µg/m3 0 ± 2 −2 ± 0.6 0.3 ± 1 −0.4 ± 0.9 −1 ± 1
PCA variability
    Air 3 ± 1 −0.01 ± 0.48 0.7 ± 0.6 −0.2 ± 0.4 −0.1 ± 0.5 NS
    10 µg/m3 4 ± 1 −0.6 ± 0.4 −0.4 ± 0.5 0.2 ± 0.9 −0.03 ± 0.72
    25 µg/m3 4 ± 0.7 0.1 ± 0.4 0.5 ± 0.7 −0.1 ± 0.3 0.4 ± 0.5
ST in lead II (µV)
    Air −20 ± 8 −0.3 ± 4 0.7 ± 6 0.8 ± 3 0 ± 5 NS
    10 µg/m3 −18 ± 12 0.7 ± 5 2 ± 4 −1 ± 3 −3 ± 5
    25 µg/m3 −17 ± 7 2 ± 5 1 ± 4 −0.7 ± 2 0.5 ± 2
ST in V2 (µV)
    Air −19 ± 7 −7 ± 4 −5 ± 4 −12 ± 5 −11 ± 5 NS
    10 µg/m3 −19 ± 5 −4 ± 4 −2 ± 2 −10 ± 5 −4 ± 5
    25 µg/m3 −25 ± 6 −6 ± 4 −3 ± 3 −8 ± 5 −6 ± 3
ST in V5 (µV)
    Air −10 ± 5 −3 ± 3 −2 ± 4 7 ± 5 −0.6 ± 4 NS
    10 µg/m3 −14 ± 7 −3 ± 4 −2 ± 3 11 ± 4 2 ± 4
    25 µg/m3 −16 ± 5 −4 ± 4 −5 ± 3 7 ± 4 2 ± 2