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. 2010 May 3;189(3):397–398. doi: 10.1083/jcb.201004022

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© 2010 Arikkath

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 1. — N-cadherin promotes dendritic spine stability. (A) Spines are dynamic and undergo formation and elimination, leading to spine turnover. These spines have relatively small postsynaptic densities and PSD-95 puncta. (B) Synaptic activity promotes the localization of N-cadherin to activated synapses. (C) Activated synapses expressing N-cadherin are stabilized, have large postsynaptic densities, and express large PSD-95 puncta.