Table 4.
Four-year Progression | |||||||||
---|---|---|---|---|---|---|---|---|---|
Age at baseline (years) |
Any Cortical Opacities |
Any Nuclear Opacities |
Any PSC* Opacities |
||||||
N† | n‡ | % (CI¥) | N | n | % (CI) | N | n | % (CI) | |
40-49 | 32 | 3 | 9.4 (0.0, 19.5) | 8 | * | * | 3 | * | * |
50-59 | 100 | 13 | 13.0 (6.4, 19.6) | 21 | 1 | 4.8 (0.0, 13.9) | 10 | * | * |
60-69 | 185 | 11 | 5.9 (2.5, 9.4) | 92 | 4 | 4.4 (0.2, 8.5) | 29 | 2 | 6.9 (0.0, 16.1) |
70+ | 130 | 11 | 8.5 (3.7, 13.3) | 121 | 4 | 3.3 (0.1, 6.5) | 27 | * | * |
P-value (trend test) | 0.33 | 0.95 | 0.78 | ||||||
Overall | 447 | 38 | 8.5 (5.9, 11.1) | 242 | 9 | 3.7 (1.3, 6.1) | 69 | 2 | 2.9 (0.0, 6.9) |
PSC=posterior subcapsular
N=number at risk at baseline
n=number of progression cases
CI=confidence interval
No progression cases.
Note: Progression defined as ≥ 2-step increase in score in at least one eye for a specific type of lens opacity, and exclude persons with scores ≥ C4 (for cortical opacity), ≥ N3 (for nuclear opacity), or ≥ P3 (for PSC opacity) at baseline.