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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: Biochem Pharmacol. 2010 Mar 30;80(2):197–204. doi: 10.1016/j.bcp.2010.03.023

Fig. 1.

Fig. 1

Loss of a single ahr allele results in reduced levels of functional AHR as assessed by TCDD induction of CYP1A1 mRNA. Cardiac CYP1A1 mRNA expression was measured by real time PCR from ahr+/+, ahr+/− and ahr−/− male mice 72 hrs after exposure to control or a total of 320 ng TCDD/kg (n=3/genotype). Data represent mean ± SEM and were analyzed by two-way ANOVA, using post hoc Holm-Sidak comparisons; *p < 0.05, compared to ahr+/+ in the same treatment; †p < 0.05 compared to ahr+/− in the same treatment; #p < 0.05 compared to control-treated mice of the same genotype.