Table 3.
Cx (n = 5–14) | LBW (n = 8–9) | SSRI-LBW (n = 6–8) | |
---|---|---|---|
Glycogen and GLUT4 protein content in RG and WG gastrocnemius muscle tissue | |||
Basal glycogen WG, μmol/g muscle wet wt | 38.8 ± 1.3 | 40.5 ± 1.7 | 42.9 ± 1.8 |
Basal glycogen RG, μmol/g muscle wet wt | 31.4 ± 2.2* | 33.8 ± 1.7* | 32.4 ± 2.3* |
Total GLUT4 content WG, arbitrary units | 9.89 ± 3.36 | 10.32 ± 0.90 | 9.97 ± 0.58 |
Total GLUT4 content RG, arbitrary units | 13.93 ± 0.71* | 16.38 ± 1.92* | 13.22 ± 0.98* |
PKB Ser473phosphorylation in RG muscle tisssue | |||
Basal phosphorylation, arbitrary units | 29,568 ± 3,239 | 31,691 ± 4,901 | 22,459 ± 4,429 |
Clamp phosphorylation, arbitrary units | 69,596 ± 10,600† | 56,729 ± 7,641† | 76,127 + 8,287†‡ |
Insulin-stimulated increase from basal, % | 135 ± 4 | 79 ± 24 | 239 ± 43§ |
Data are means ± SE. RG, red gastrocnemius; WG, white gastrocnemius. P values for comparisons reflect the results for the post hoc analysis that has been carried out only when the 1-way ANOVA test results in a P value <0.05. Post hoc test P values:
P < 0.05 vs. WG;
P < 0.05 vs. basal;
P < 0.10 vs. LBW;
P < 0.05 vs. LBW.