Fig. 5.
Surfactant phospholipid composition is altered in newborn Abca3Δ/Δ mice. A: saturated phosphatidylcholine (Sat PC) was decreased in whole lung tissue from PND0 Abca3Δ/Δ mice. *P < 0.05. B and C: relative distribution of phosphatidylcholine (PC) and lysophosphatidylcholine (LPC), sphingomyelin (SM), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylinositol (PI), phosphatidylglycerol (PG), and bis(monoacylglycerol)phosphate (BMPA) in lung tissue from PND0 Abca3Δ/Δ and control littermates as determined by 2-dimensional thin-layer chromatography, as described previously (26). Values are means ± SE of 4 animals per group. *P < 0.05.