Table 1.
Alterations in gene expression after deletion of Abca3 in type II epithelial cells
| Gene | Reference Sequence ID | Description | Ratio |
|---|---|---|---|
| Aqp3 | 1422008_a_at | Aquaporin 3 | −7.092 |
| Sftpa1 | 1429626_at | Surfactant-associated protein A1 | −3.953 |
| Gjb6 | 1448397_at | Gap junction membrane channel protein-β6 | −3.636 |
| Aqp5 | 1418818_at | Aquaporin 5 | −3.195 |
| Lipg | 1421262_at | Lipase, endothelial | −2.445 |
| Pnliprp1 | 1415777_at | Pancreatic lipase-related protein 1 | −2.155 |
| Lpcat1 | 1424460_at | Lysophosphatidylcholine acyltransferase 1 | −2.114 |
| Rab27a | 1429123_at | Rab27a member RAS oncogene family (GTP-binding) | −1.898 |
| Pnpla2 | 1428591_at | Patatin-like phospholipase domain-containing 2 | −1.587 |
| Sc5d | 1434520_at | Sterol-C5-desaturase homolog | +1.712 |
Differences in mRNAs in the lung of embryonic day 18.5 Abca3Δ/Δ and control mice were identified through microarray analysis. Genes most changed after deletion of Abca3 are shown. Differentially expressed genes were identified using a univariate F test and a permutation test (n = 100) with a significance level of 0.05.