Skip to main content
. 2010 Feb 19;298(5):L637–L645. doi: 10.1152/ajplung.00414.2009

Fig. 4.

Fig. 4.

LPS stimulates microvascular endothelial cell angiogenesis and migration. A–C: mouse lung microvascular endothelial cells were cultured for 20 h in control Matrigel (A) or Matrigel containing E. coli LPS (250 ng/ml; B). C: the lengths of endothelial cell tubes were measured between branch points and normalized to control (*P < 0.001; n = 31). D: LPS increased migration of microvascular endothelial cells through Boyden chamber membranes. (*P < 0.001; n = 18). E: LPS increased wound healing in cultured microvascular endothelial cells. LPS was added either at the time of wounding (LPS) or 24 h before wounding (LPS pretx). Wound healing was measured 24 h after wounding (*P < 0.05; n = 41). Error bars ± standard error of the mean. Norm, normal; ctrl, control.