Fig. 1.

Betaine supplementation had no effect on body weight change and food consumption in C57BL/6 mice fed a high-fat diet. A: changes of absolute body weight. B: changes of body weight gain. C: daily food consumption. C57BL/6 mice were fed with control and high-fat diet with/without betaine supplementation (1%) in the drinking water (n = 8 mice/group) for 12 wk. Con, control diet; BT, control diet supplemented with betaine in the drinking water; HF, high-fat diet; HB, high-fat diet supplemented with betaine in the drinking water. Data are means ± SD (n = 8). Bars with different letters differ significantly (P < 0.05).