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Betaine supplementation improved adipokine production in mice fed a high-fat diet. A: circulating adiponectin levels. B: circulating leptin levels. C: circulating resistin levels. C57BL/6 mice were fed a high-fat diet with/without betaine supplementation (1%) in drinking water for 12 wk. Data are means ± SD (n = 8). Bars with different letters differ significantly (P < 0.05).
