Table 1.

Summary of statistical analysis of all parameters measured in the comprehensive laboratory animal monitoring system

		Week 0 LD	Week 8 SD	Week 16 SD	Week 4 LD
Activity (successive beam breaks)	n*	8	1	3	8
	A†	108 ± 14	31 ± 7	33 ± 9	81 ± 18
Oxygen consumption	n*	8	0	3	7
	A†	328 ± 51	105 ± 22	179 ± 36	293 ± 45
Carbon dioxide output	n*	8	1	4	7
	A†	250 ± 37	91 ± 18	165 ± 24	245 ± 38
Respiratory quotient	n*	8	5	2	8
	A†	0.04 ± 0.003	0.03 ± 0.006	0.02 ± 0.004	0.06 ± 0.004
Meal frequency‡		F = 10.8, P < 0.0001	ns	ns	F = 4.92, P < 0.0001
Meal duration‡		F = 8.54, P < 0.0001	F = 2.50, P < 0.001	F = 2.37, P < 0.05	F = 10.6, P < 0.0001
Total food intake‡		ns	F = 4.92, P < 0.0001	F = 2.12, P < 0.05	F = 3.53, P < 0.001

^*Number of animals out of a total of 8 for which a single cosine nonlinear regression significantly fits the data for the indicated locomotor activity or gas exchange variable.

^†Values are expressed as means ± SE amplitude of the best-fit cosinor curve for each hamster (n = 8).

^‡Repeated-measures ANOVA to determine the effect of time on each parameter of ingestive behavior; n = 8 hamsters on each sampling occasion.