Table 4.
Predicted target genes of miRNAs that are most affected in expression by development
| miRNA | Fold Change | Predicted Target Genes |
|---|---|---|
| 431 | 26 | DMN, Mtap1b, Adam 18, Fgl2, Adcy7 |
| 134 | 18 | Pex13, Tcf21, PLD1, Chsy1, CUL5, IL-7, VEGFA, Agtrl1 |
| 541 | 14 | USp15, StK3, Anxa1, FGF1 |
| 433 | 10 | Sema6a, Enth, CCar1, MapK8, ApoF |
| 409-3p | 10 | Notch1 induced protein, USp33, Cntn4, Zeb1, Matr3 |
| 381 | 9.8 | Arid4b, Stx12, PdpN, Ccnt2, Jag2, CO111A1 |
| 299 | 7.5 | Sema3d, Usp9x, Ppm1l, E1n, MapK8 |
| 127 | 7.4 | Cisd1, Sept7, Cntn4 |
| 494 | 6.3 | Pdcl3, Sept9, Fgfr2, CyclinT2, COL12A1 |
| 337 | 6.3 | (See Table 2) |
| 351 | 6.1 | Slitrk6, ItgA7, STAT3, Bmf |
| 29c | −5.9 | (See Table 1) |
| 189 | −4.6 | (See Table 1) |
| 497 | −3.4 | Spna1, Rai2, Ccnt2, MapK8, COL24A1, VEGFA, SgK1 |
| 29b | −3.4 | COL4A5, COL9A1, COL3A1, COL5A2, Serpin5, E1n, Igf1, VEGFA, PCDH subtypes |
| 29a | −1.9 | COL4A5, COL9A1, COL3A1, Eln, IGFA1, DUSP2, PCDH subtypes |
| 140 | −1.5 | FGF9, SnX2, Sept2, PDGFRA, Lrp4, VEGFA, VEGFD |
Fold changes (P1/12 mo) are comparison of P1 levels of miRNA in both control and MUN as compared with 12-mo-old group expression. Positive numbers signify greater expression in P1 as compared with 12-mo-old group levels and negative numbers signify the opposite.