Table 2.
Oxidized and reduced glutathione concentrations in whole blood samples
Control | Fructose | Fructose + LA | ||||
---|---|---|---|---|---|---|
Age, mo | 2 | 4 | 2 | 4 | 2 | 4 |
GSH, μM | 2736 ± 239 | 1904 ± 148 | 2607 ± 166 | 1703 ± 113 | 2636 ± 176 | 2211 ± 125* |
GSSG, μM | 69 ± 4 | 61 ± 4 | 71 ± 3 | 59 ± 3 | 73 ± 2 | 69 ± 3* |
GSH/GSSG | 38 ± 3 | 31 ± 3 | 35 ± 2 | 27 ± 1** | 34 ± 2 | 31 ± 2 |
Values are expressed as means ± SE; P < 0.05 by one-factor ANOVA,
P < 0.05 compared to fructose by Bonferroni's post test and
P < 0.05 compared to baseline (2-mo) ratio by Student's t-test. Excludes animals that became diabetic and began losing weight before 4 mo of age. Control: n = 10, fructose: n = 10, fructose + LA: n = 11.