Table 1.
Summary of the localization of connexin isoforms in the kidney
| Cx | Renal Localization | Cell Type | Species | References |
|---|---|---|---|---|
| 26 | Proximal tubule* | Epithelial | Mouse | 10 |
| 30 | Distal nephron | Epithelial | Rat | 80 |
| Cortical CD, CNT | Intercalated | Mouse, rabbit, rat | 80 | |
| 30.3 | ATL | Epithelial | Mouse, rabbit, rat | 42,148 |
| Cortical CD | Intercalated | Mouse, rabbit, rat | 42,148 | |
| 32 | Proximal tubule* | Epithelial | Mouse | 10 |
| 37 | Arcuate artery; IA* | VSMC | Mouse | 144 |
| RA; AA | Endothelial | Mouse, rat | 1,7,56,109 | |
| EA | Endothelial | Rat | 121 | |
| Vasa recta | Pericytes | Rat | 147 | |
| Vascular bundles | Endothelial | Mouse | 144 | |
| Vascular pole | Mesangial | Mouse | 52,56,144 | |
| JGA* | Granular, mesangial | Mouse, rat | 56,69,121,144 | |
| Proximal tubule | Epithelial | Mouse, rat | 118 | |
| TAL | Endothelial | Mouse, rat | 118 | |
| DCT | Endothelial | Mouse, rat | 118 | |
| CNT | Principal cells > Intercalated | Mouse, rat | 118 | |
| CD | Principal cells > Intercalated | Mouse, rat | 118 | |
| 40 | RA; Arcuate artery; IA; AA | Endothelial | Mouse, rat | 1,38,52,56,129 |
| Vasa recta | Endothelial | Rat | 147 | |
| Vascular bundles | Endothelial | Mouse | 144 | |
| Glomerulus | Endothelial,* mesangial | Mouse | 52,56,144 | |
| JGA | Endothelial,* granular, mesangial | Mouse, rat | 1,52,69,121,144 | |
| 43 | RA, AA | Endothelial, VSMC* | Mouse, rat | 1,52,144 |
| EA | Endothelial | Mouse | 144 | |
| Peritubular capillaries | Endothelial | Mouse | 144 | |
| Vascular bundles | Endothelial | Rat | 3 | |
| Vasa recta | Endothelial | Rat | 147 | |
| Renal veins | Endothelial | Mouse | 69 | |
| Glomerulus | Podocytes | Human | 103 | |
| Proximal tubule | Epithelial | Human | 133,134 | |
| Inner medullary CD* | Epithelial | Rat | 3,34 | |
| 45 | IA, AA | VSMC | Mouse | 43,56,64,69,105 |
| EA | VSMC | Mouse | 43,56,64,69,105 | |
| Glomerulus | Mesangial, podocytes | Mouse | 10,43,56,69,105 | |
| JGA | Granular,* mesangial | Mouse | 43 |
ATL, ascending thin limb of the loop of Henle; AA, afferent arteriole; CD, collecting duct; CNT, connecting tubule; DCT, distal convoluted tubule; EA, efferent arteriole; IA, interlobular artery. JGA, juxtaglomerular apparatus; TAL, thick ascending limb of the loop of Henle; VSMC, vascular smooth muscle cell. >, Stronger than.
*
Conflicting localization data.