Fig. 3.

Ratios of total perimeter per high-power field (HPF) to septal wall thickness. Top: pups were exposed to prenatal saline or LPS and postnatal room air (open bars) or 85% O₂ (solid bars) for 14 days, and ratio was measured at day 14. Bottom: pups were exposed to prenatal saline or LPS and postnatal room air (open bars) or 85% O₂ (solid bars) for 14 days, followed by 14 days recovery, and ratio was measured at day 28. Data were analyzed by 2-way ANOVA with modified t-test post hoc (n = 6 per group). Effects of prenatal LPS, postnatal hyperoxia exposure, and an interaction between prenatal LPS and postnatal hyperoxia exposure were observed. Values are means ± SE. Identical symbols above bars indicate statistical significance between groups: *P ≤ 0.05; $,§,†,‡P ≤ 0.01.