Table 2.
Comparison of model predictions to literature values of perfusion measures
| Reference | Literature Values | Circuit Model A | Circuit Model B | |
|---|---|---|---|---|
| PAP at rest, mmHg | 18 | 10 (diastolic), 25 (systolic) | 17–25 (input) | 17–25 (input) |
| LAP at rest, mmHg | 8, 11, 35 | 4.0–10 | 7 (input) | 7 (input) |
| PVR, dyn · s · cm−5 | 36 | <240 | 286 | 235 |
| Flow through lungs at rest, l/min | 11, 22, 30 | 4.0–6.5 | 2.8–5.0 | 3.4–6.1 |
| % Pressure drop through arteries | 1, 9, 20 | 20–50 (dog) | 22.6 | 23.1 |
| % Pressure drop through acinus | 82.7 | 79.1–79.0 |
Units are converted from SI units to those commonly used in the literature. Because pulmonary arterial pressure (PAP) varies over a heartbeat, a range of values for this parameter was used for model input. Output values given correspond to the extremes of the range for input PAP. LAP, left atrial pressure; PVR, pulmonary vascular resistance.