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. 2010 Feb 24;103(5):2417–2432. doi: 10.1152/jn.01143.2009

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Fig. 7. — Fast excitatory synaptic transmission on PPN thalamic projecting neurons. A: the frequency of spontaneous excitatory PSCs (EPSCs) recorded in the presence of GBZ and STR (a) was not significantly changed after APV application (b) but was abolished by CNQX (c) and recovered after wash (d and e). B: the amplitude of evoked EPSCs in a PPN output neuron (1st record) was not significantly attenuated by APV (2nd record) but was blocked by CNQX (3rd record), which recovered after washing in GBZ and STR (4th record). Gray records represent the average of 10 individual trials (black records) in each condition. This result indicates that fast excitatory synaptic transmission to PPN thalamic projecting neurons was mainly modulated by AMPA/kainate receptors in our experimental conditions.