Table 2.
Relative levels of hemoglobin-derived peptides in Cpefat/fat mice.
| Protein | Sequence | Brain Region | Cpefat/fat:WT ± SEM (n) |
|---|---|---|---|
| Alpha Hemoglobin | |||
| LSDLHAHKL | Olf Bulb | 3.65 ± 1.06 (4) | |
| VDPVNFKLLSH | Olf Bulb | 4.81 ± 3.31 (2) | |
| AGHLDDLPGALSAL | Olf Bulb | 6.91 ± 5.39 (2) | |
| RVDPVNFKLLSH | Olf Bulb | 3.43 ± 0.68 (8) | |
| RVDPVNFKLLSH | PFCx | 1.20 ± 0.19 (3) | |
| RVDPVNFKLLSH | Striatum | >6 (4) | |
| ASHHPADFTPAVHA | Olf Bulb | 3.37 ± 1.72 (2) | |
| ANAAGHLDDLPGALSAL | Olf Bulb | 7.18 ± 5.42 (2) | |
| KFLASVSTVLTSKYR | PFCx | 1.20 ± 0.21 (2) | |
| (FTPAVHASLDKFLASVSTVLTSKYR) | PFCx | 1.31 ± 0.31 (2) | |
| Beta Hemoglobin | |||
| VVYPWTQRY | Hypo | >10 (2) | |
The relative levels of peptides were calculated by the ratio of peak intensity of the D0-TMAB-and the D9-TMAB-labeled peptide pairs. Cpefat/fat:WT indicates the ratio of peptide in Cpefat/fat mice relative to WT mice with standard error of the mean (SEM) for n replicates. Abbreviations: Olf Bulb, olfactory bulb; PFCx, prefrontal cortex; Hypo, hypothalamus; ND, not detected.