Fig 2.
Lack of effect of local anaesthetics on repair in a model of impaired healing. (a) Day 3 wound areas in ovariectomized (OVX) mice treated before operation with lidocaine or bupivacaine (or vehicle). (b) Percentage re-epithelialization of day 3 wounds from LA-treated and control OVX animals. Values are expressed as mean (sem). n=7–8 per treatment group. Statistical significance was tested by one-way anova (a) and the Kruskal–Wallis test (b). Bup., bupivacaine; Con, control (vehicle: sterile dH2O); Lid., lidocaine; Re-ep., re-epithelialization.