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. 2010 Apr 5;107(16):7473–7478. doi: 10.1073/pnas.1002650107

Table 1.

Patient characteristics

Patient characteristic Result
Median age (years) 74 (range, 60–85)
  6 patients, 60–65 years
  35 patients, 65–79 years
  8 patients, ≥80 years
Male/Female (n) 34/19
AML rising from AHD (n) 13
t-AML (N) 6
Median presenting WBC count, ×103/μL 2.7 (range, 0.4–150.0)
Median BM blasts,% 52 (range, 20–92%)
Cytogenetics (n)
  CBF 1, patient had t(8;21)(q22;q22),,−7
  Normal karyotype 21
  Complex karyotype 16 (12 with ≥5 abnormalities)
  Other 13
MRC* prognostic risk score, percent of patients
  Good 19
  Standard 32
  Poor 49

AHD, antecedent hematologic disorder; BM, bone marrow; CBF, core binding factor; n, number of patients; t-AML, therapy-related AML.

*See ref. 17.