Table 1.
Patient characteristic | Result |
Median age (years) | 74 (range, 60–85) |
6 patients, 60–65 years | |
35 patients, 65–79 years | |
8 patients, ≥80 years | |
Male/Female (n) | 34/19 |
AML rising from AHD (n) | 13 |
t-AML (N) | 6 |
Median presenting WBC count, ×103/μL | 2.7 (range, 0.4–150.0) |
Median BM blasts,% | 52 (range, 20–92%) |
Cytogenetics (n) | |
CBF | 1, patient had t(8;21)(q22;q22),,−7 |
Normal karyotype | 21 |
Complex karyotype | 16 (12 with ≥5 abnormalities) |
Other | 13 |
MRC* prognostic risk score, percent of patients | |
Good | 19 |
Standard | 32 |
Poor | 49 |
AHD, antecedent hematologic disorder; BM, bone marrow; CBF, core binding factor; n, number of patients; t-AML, therapy-related AML.
*See ref. 17.