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. 2010 Apr 5;107(16):7473–7478. doi: 10.1073/pnas.1002650107

Table 2.

Nonhematologic toxicities, grade ≥3 experienced during the first two cycles of treatment

Toxicity Patients with grade ≥ 3 in cycles 1 and 2 (n)
Infection
  Documented infection 31
  Febrile neutropenia 5
Constitutional
  Fatigue 3
  Fever 2
Gastrointestinal
  Anorexia 1
  Dysgeusia 1
  Mucositis/gingivitis 3
Pulmonary
  Dyspnea 3
  Hypoxia 8
Cardiac
  Prolonged QTc 2
  Decreased left ventricular ejection fraction 1
  Arrhythmia 3
  Hypertension 2
Skin
  Decubitus ulcer 1
  Rash 2
Neurologic
  Confusion 1
  Syncope 3
  Abnormal gait 2
Other
  Pain 7
  Thrombosis 3
  Hemorrhage/hematoma 5