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. 2010 Apr 5;107(16):7598–7603. doi: 10.1073/pnas.0913492107

Fig. 2.

Fig. 2.

Phenotypic analyses of mice lacking Acc2 in skeletal muscle. (A) Immunoblot analyses of 50 mcg muscle lysates from mice homozygous for the floxed Acc2 allele without (fl/fl) and with (fl/fl; Cre) the muscle-specific Cre (MyoCre) transgene and mice heterozygous for the floxed allele with the muscle-specific Cre transgene (fl/+; Cre). Blots were probed with the anti-ACC polyclonal antibody. (B) Bodyweight and food intake were assessed weekly. Body composition analysis was performed at 22 weeks. Data are represented as % fat mass (fat mass/body mass × 100) and % lean mass (lean mass/body mass × 100). (C) Ambient blood glucose and insulin levels were determined 2 hr following the removal of food. Flox/Flox n = 11; MyoCre x Flox/Flox n = 10.