Fig. 3.

Phenotypic analysis of global Acc2KO mice fed regular chow diet. (A and B) Bodyweight and food intake were determined weekly. (C) Body composition data are represented as % fat mass and % lean mass. (D) Wet heart weights were measured and are expressed per g animal body weight. (E and F) Ambient blood glucose and insulin levels were obtained from tail bleeds within 2 hr of food withdrawal. (G) Glucose tolerance test using glucose 2 g/kg injected i.p. following an overnight fast (16 h). There was no difference in body weights between Acc2KOs (34.1 ± 1.4 g, n = 9) and controls (32.8 ± 0.9 g, n = 7), P = 0.49.