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. 2008 Aug 20;26(24):3937–3942. doi: 10.1200/JCO.2008.16.5043

Table 2.

Unadjusted and Adjusted Odds Ratios of Recommending Adjuvant RT for Stage I Seminoma for Each Clinical and Patient Characteristic

Covariate No. of Patients (men) RT (%)
Univariable
Multivariable
Recommended Not Recommended Odds Ratio 95% CI P Odds Ratio 95% CI P
Year of diagnosis (per year increase) 3,125 0.96 0.94 to 0.98 < .001 0.93 0.91 to 0.96 < .001
Median age at diagnosis (per year increase), years 3,125 36 35 1.01 1.00 to 1.02 .111 1.01 1.00 to 1.02 .127
    Range 17-81 13-82
Proportion of county (age > 25) with less than a high school education (per % increase) 3,125 15.4 15.6 0.96 0.95 to 0.98 < .001 0.95 0.93 to 0.96 < .001
    Range 3.7-41.5 6.3-42.2
Race
    White 2,876 81.0 19.0 1.0* 1.0*
    Nonwhite 249 83.1 16.9 1.16 0.82 to 1.63 .413 1.20 0.84 to 1.71 .322
SEER region
    South 258 78.7 21.3 1.0* 1.0*
    West 1,644 83.2 16.9 1.34 0.97 to 1.85 .080 1.43 1.03 to 1.98 .034
    Midwest 782 80.7 19.3 1.13 0.80 to 1.60 .483 1.36 0.95 to 1.95 .089
    Northeast 441 76.2 23.8 0.87 0.60 to 1.26 .449 1.02 0.70 to 1.48 .935
Tumor category
    T1 2,451 80.8 19.2 1.0* 1.0*
    T2 604 83.0 17.1 1.15 0.91 to 1.46 .232 1.27 0.99 to 1.62 .057
    T3/T4 70 78.6 21.4 0.87 0.49 to 1.55 .638 0.86 0.48 to 1.56 .620
Tumor size, cm
    ≤ 4 1,872 80.3 19.7 1.0* 1.0*
    > 4 1,253 82.4 17.6 1.15 0.96 to 1.38 .141 1.12 0.92 to 1.35 .257

Abbreviations: RT, radiation therapy; SEER, Surveillance Epidemiology and End Results.

*

This group served as the reference group in the logistic regression analysis.