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. 2010 Apr 12;107(17):8011–8016. doi: 10.1073/pnas.0912901107

Fig. 5.

Fig. 5.

Relative permeability properties in isolated perfused S2 segments of proximal tubules from Cldn2+/+ and Cldn2−/− kidneys. (A) Representative tracings of the transepithelial voltage (VT) on reducing luminal NaCl. (B) Relative permeability of Na+ to Cl– (PNa/PCl). Values are mean ± SEM of 76 Cldn2+/+ proximal tubules and 82 Cldn2−/− proximal tubules. *P < 0.001 vs. Cldn2+/+ tubules. (C) Relative permeabilities of cations and anions to Cl– (PX/PCl). Values are mean ± SEM of 11 Cldn2+/+ proximal tubules and 10 Cldn2−/− proximal tubules. *P < 0.001, †P < 0.05 vs. Cldn2+/+ tubules.