Table 1.

Electrical properties in isolated perfused S2 segments of proximal tubules from Cldn2^+/+ and Cldn2^−/− mice

	+/+	−/−
No. of tubules	44	48
Tubular length, μm	772.4 ± 23.8	788.7 ± 20.4
Tubular radius, μm	13.0 ± 0.2	12.9 ± 0.2
RT, Ωcm2	11.3 ± 0.4	25.2 ± 1.0*
fRA	0.72 ± 0.01	0.73 ± 0.01
VT, mV	−0.91 ± 0.13	−0.62 ± 0.13
VB, mV	−65.1 ± 1.1	−66.4 ± 1.5

Values are mean ± SEM. fR_A, fractional apical membrane resistance; R_T, transepithelial electrical resistance; V_B, basolateral membrane voltage; V_T, transepithelial voltage.

*P < 0.001 vs. Cld2^+/+ tubules.