. Author manuscript; available in PMC: 2011 Apr 9.

Published in final edited form as: J Mol Biol. 2010 Feb 12;397(4):893–905. doi: 10.1016/j.jmb.2010.02.015

Table 5.

Fold change in each parameter required to abolish the overshoot in active FNR during the aerobic-to-anaerobic transition

	Parameter
	α_1,max/α₁	α₂₁	α₂₂	β_1,off/β_1,on	β_21,off/β_21,on	β₂₂	β_31,off/β_31,on	g₁₃	X₄	X₅
Tolerated increase	∞	∞	∞	2.47	1.37	2150	6930	∞	1.37	2150
Tolerated decrease	∞	2.49	1080	3 × 10⁸	∞	12,000	1.6	4.6 × 10⁷	∞	12,000

The parameters are as follows: α_1,max/α₁ (transcription rate), α₂₁ (translation rate), α₂₂ (rate of disassociation of active FNR dimer), β_1,off/β_1,on (rate of mRNA degradation), β_21,off/β_21,on (rate of degradation of inactive FNR monomer), β₂₂ (rate of dimerization), β_31,off/β_31,on (rate of degradation of active FNR dimer), and g₁₃ (kinetic order of repression of mRNA synthesis).