Table 2. Data derived from Fajara, Western Region studies.
Ref. | Location | Year | Population & (person-years) denominators | NTS isolates | Pneumococcal isolates | NTS incidence <5 years* | IPD incidence <5 years* | Percentage malaria slides positive | Percentage malaria admissions |
[4] | Fajara | 1979–84 | 20000 (115000) | 69 | 38 | 60 | 33 | n/a | n/a |
[12] | Western | 1993–95 | (64181, 0–3 years) | 39† | 76‡ | 36§ | 70∥ | n/a | n/a |
[13] | Fajara | 2003–05 | 38322 (51096) | 5 | 29 | 10 | 57 | n/a | n/a |
† | Fajara | 19821994 | n/a | n/a | n/a | n/a | n/a | 22%32% | |
[11] | Fajara | 19992001200320052007 | n/a | n/a | n/a | n/a | n/a | 33%32%22%8%6% | 14.5%20.5%17%8.5%5% |
Note: * Incidence per 100000 person-years.
†Authors' unpublished data (BG).
‡76/116 (66%) pneumococcal isolates were from blood cultures.
§As estimates of age-specific NTS infection are not available, the incidence of NTS disease is estimated from the ratio of NTS to pneumococcal isolates, 39:76 = 0.51, and the estimated incidence of pneumococcal blood stream infection.
∥Incidence of pneumococcal blood stream infection is calculated from values reported by Usen et al. 1998 [12] and the proportion of IPD due to blood stream infection (0.66), as 0–1 yr: 178×0.66 = 117, 2 yrs: 86×0.66 = 57, 3–4 yrs: extrapolated as half the incidence among those 2 yrs of age; 57/2 = 29, <5 yrs: [(117×2)+57+(29×2)]/5 = 70. § Incidence of NTS disease is calculated as 70×0.51 = 36.