Table 4.
Results of the discriminatory immunohistochemistry in historical TSE cases from passive surveillance.
| Samples | ID | CNS region | Intraneuronal PrPd labeling | |
|---|---|---|---|---|
| MAb R145 | MAb12B2 | |||
| Controls | Classical scrapie | Obex | +++ | +++ |
| BSEov - 1 | Obex | +++ | - | |
| BSEov - 2 | Spinal cord | +++ | - | |
| BSEov - 3 | Spinal cord | +++ | - | |
| TSE-negative | Obex | - | - | |
| Pre-surveillance | 15355 | Obex | +++ | +++ |
| Passive surveillance | 21658 | Hippocampus | + | +++ |
| 22614 | Midbrain | + | ++ - +++ | |
| 22805 | Midbrain, hippocampus | + | ++ | |
| 22856 | Obex | - | - | |
| 24058 | Cerebral cortex | - | - | |
| 30842 | Spinal cord | + - ++ | +++ | |