Table 1.
Demographic data of the study population and the results of lung function tests.
| All n (%) |
R cases (n = 574) |
NR cases (n = 431) |
S cases (n = 334) |
|
|---|---|---|---|---|
| Men (%) | 48 | 52 | 44 | 49 |
| Smoking status | ||||
| Smokers, no. (%) | 737 (55) | 423 (74) | 177 (41) | 137 (41) |
| Never-smokers no. (%) | 602 (45) | 151 (26) | 254 (59) | 197 (59) |
| Respiratory symptoms at inclusion, no. (%) | 839 (63) | 574 | 166 (38) | 99 (30) |
| Deaths, no. (%) | 315 (24) | 212 (37) | 79 (18) | 24 (7) |
| Lung transplant (no.) | 56 | 51 | 3 | 2 |
| Liver transplant (no.) | 2 | - | 2 | - |
| Mean (range) age at diagnosis (years) | 41 (0-88) | 51 (0.1-88) | 40 (0.01-84) | 24 (0-77) |
| Mean (range) age at inclusion (years) | 47 (18-89) | 54 (18-89) | 45 (18-87) | 35 (18-78) |
| Mean (range) follow-up time (years) | 9 (0.02-17) | 8 (0.02-17) | 10 (0.02-17) | 11 (0.07-17) |
| Mean age (range) at death | 67 (20-95) | 67 (30-95) | 69 (20-90) | 61 (37-85) |
| Mean (SD) FEV1 (% predicted) | 72 (33) | 50 (29)* | 88 (25) | 89 (23) |
| Mean (SD) FVC (% predicted) | 84 (23) | 75 (25)* | 89 (18) | 93 (16) |
| Mean (SD) FEV1/FVC ratio (%) | 63 (23) | 48 (22)* | 75 (17) | 76 (15) |
R: respiratory. NR: non-respiratory. S: screened.
*p < 0.001 vs. NR cases and S cases.