Table 4.
Multivariable Cox Regression Models for Survival in PiZZ Individuals*
| No. | Risk Ratio | 95%CI | P value | |
|---|---|---|---|---|
| Gender | 0.90 | |||
| Male | 635 | 1.00 | 0.80-1.30 | 0.90 |
| Female | 674 | 1.0 | ||
| Age at inclusion, years | <0.001 | |||
| >50 | 580 | 5.50 | 4.0-7.50 | <0.001 |
| ≤50 | 729 | 1.0 | ||
| Pre-bronchodilator FEV1 % of predicted | <0.001 | |||
| 183 | 4.30 | 2.90-6.40 | <0.001 | |
| < 30 | 230 | 2.00 | <0.001 | |
| 30-49 | 263 | 1.60 | 1.40-3.00 | 0.020 |
| 50-79 | 633 | 1.0 | ||
| ≥ 80 | 1.10-2.40 | |||
| Respiratory symptoms at inclusion& | 0.001 | |||
| Yes | 820 | 2.20 | 1.40-3.50 | 0.001 |
| No | 489 | 1.0 |
** 1309 individuals with complete data on included predictors.
&irrespective of mode of identification.