Table 1.
Model parameters
| Base case | Range | Source | |
|---|---|---|---|
| Duration of carriage (days): | [41,42] | ||
| 0-1 y | 72 | ||
| 2-4 y | 28 | ||
| 5-17 y | 18 | ||
| 18+ y | 17 | ||
| cV | 0.5 | 0-1 | [41] |
| cN | 0.85* | 0.5-1 | *Fitted to US data |
| ε, mixing pattern | 0.87* | 0.7-0.95 | *Fitted to US data |
| 1/ω, average duration of protection | 8.3 y* | 5-20 y# | *Fitted to US data #95% CI estimated |
| γ, degree of protection | 0.756* | 69-84%#^ | *Fitted to US data #95% CI estimated |
^duration and degree of protection are correlated; i.e. short duration is paired with high protection
Transmission parameters of pneumococcal carriage for the base case and ranges used in the sensitivity analyses.