Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 May 11;5(5):e10583. doi: 10.1371/journal.pone.0010583

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

Five to eight B6 mice per group were primed intranasally with X31 or Memphis H3N2 influenza A viruses as indicated or equal volume of allantoic fluid as control. 35 to 45 days after priming, the animals were challenged with lethal doses of heterosubtypic H1N1 influenza viruses as indicated. Body weight loss (left panel) and survival (right panel) of the animals were monitored until day 19 after lethal challenge. Animals that lost 25% of their initial body weight were considered moribund and sacrificed according the animal protocol. The results were expressed as body weight loss of individual mice per group. The numbers on the lower right corner of each graph indicate survival rate of each group (the number of animals survived/total number of animals tested).