Table 2.
Possible associations between HPV and clinicopathological parameters of colon cancer
| - | HPV % |
+ | % | |||
|---|---|---|---|---|---|---|
| MSI | MSS | 187 | 94.4 | 31 | 93.9 | 1 |
| MSI | 11 | 5.6 | 2 | 6.1 | ||
| age (median) | 56 | 60 | 0.05 | |||
| gender | male | 119 | 59.8 | 23 | 69.7 | 0.337 |
| female | 80 | 40.2 | 10 | 30.3 | ||
| grade of differentiation | good | 83 | 44.1 | 12 | 40.0 | 0.764 |
| average | 87 | 46.8 | 16 | 53.3 | ||
| poor | 17 | 9.0 | 2 | 6.7 | ||
| location | proximal | 57 | 30.3 | 13 | 39.4 | 0.565 |
| distal | 70 | 37.2 | 10 | 30.3 | ||
| rectum | 61 | 32.4 | 10 | 30.3 | ||
| lymph nodes | + | 97 | 86.6 | 82 | 89.1 | 0.670 |
| - | 15 | 13.4 | 10 | 10.9 | ||
| stage | I | 25 | 13.0 | 3 | 9.7 | 0.265 |
| II | 55 | 28.7 | 13 | 41.9 | ||
| III | 62 | 32.3 | 12 | 38.7 | ||
| IV | 50 | 26.0 | 3 | 9.7 | ||
| adjuvant | yes | 62 | 37.8 | 22 | 73.3 | 0.303 |
| no | 102 | 62.2 | 8 | 26.7 |
Possible associations were investigated using the χ2-test or Fisher's exact test (when appropriate) for categorical variables and using Student t-test or Mann-Whitney U test (when appropriate) for continuous variables (MSI: microsatellite instability, MSS: microsatellite stability)