Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
1,25D accelerates the onset of nutlin-induced apoptosis in OCI-AML3 and MOLM-13 cells. A and B. Cells were incubated with 10 nM 1,25D for 48 h followed by 10 µM nutlin-3a during the last 24 h or single agents: 10 nM 1,25D for 48 h and 10 µM nutlin-3a for 24 h. The total fraction of Annexin V- positive cells (early and late apoptotic cells) was determined using the Guava Nexin™ Kit and displayed as a dot-plot in a quadrant marker.
