Table 5.
Estimated glomerular filtration rate at follow-up (ml/min/1.73m2)
| Estimated GFR | Baseline N = 251 | 6 months FUP N = 154 | 12 months FUP N = 97 |
|---|---|---|---|
| Baseline GFR MILD e-GFR ≥ 60 | |||
| N = 82 | N = 45 | N = 29 | |
| Mean ± SD | 90.32 ± 36.59 | 85.55 ± 37.24 | 62.03 ± 26.23 |
| Improvement | 8.89% | 3.45% | |
| Stabilization | 75.56% | 58.62% | |
| Worsening | 15.56% | 37.93% | |
| Baseline e-GFR MODERATE e-GFR ≥30 <60 | |||
| N = 111 | N = 68 | N = 48 | |
| Mean ±SD | 45.37 ± 8.68 | 49.82 ± 26.87 | 47.33 ± 15.22 |
| Improvement | 27.94% | 22.92% | |
| Stabilization | 54.41% | 62.50% | |
| Worsening | 17.65% | 14.58% | |
| Baseline GFR SEVERE e-GFR <30 | |||
| N = 55 | N = 41 | N = 20 | |
| Mean ±SD | 20.61 ± 7.31 | 35.40 ± 25.46a | 36.32 ± 22.84† |
| Improvement | 51.22% | 50.00% | |
| Stabilization | 39.02% | 50.00% | |
| Worsening | 9.76% | 0.00% | |
| Overall population | |||
| N = 248 | N = 154 | N = 97 | |
| Mean ± SD | 54.74 ± 34.69 | 56.42 ± 35.66 | 49.46 ± 22.43 |
| Improvement | 28.57% | 22.68% | |
| Stabilization | 56.49% | 58.76% | |
| Worsening | 14.94% | 18.56% | |
Estimated glomerular filtration rate using Cockcroft-Gault formula [14]
a p < 0.001 (by Mc Nemar test)
Improvement = Increase of e-GFR by 20% versus baseline
Worsening = Decrease of e-GFR by 20% versus baseline
Stabilization = No worsening