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Medium-sized arteries in hearts of wild-type (+/+//+/+//+/+), AT1a- (−/−//+/+//+/+), AT1b- (+/+//−/−//+/+), and AT2- (+/+//+/+//−/−) single-knockout mice, mice exclusively expressing AT1a (+/+//−/−//−/−), AT1b (−/−//+/+//−/−), or AT2 (−/−//−/−//+/+), triple-knockout mice (−/−//−/−//−/−), and angiotensinogen-deficient (Agt −/−) mice do not show genotype-related morphological alterations (PAS-stained; magnification: 400-fold; representative sections for all groups from n ≥ 4 sections).
