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. 2010 Jan 22;86(3):374–382. doi: 10.1093/cvr/cvq023

Figure 1.

Figure 1

Scheme of the rodent ENH gene and the splice variants of its transcript. (A) Schematic representation of the genomic organization of the rat ENH gene with 18 exons. Translation start codon (Met) is located on the third exon. There are two stop codons (Ter): the first located in the 12th exon, the second in the 18th exon. The PDZ domain is encoded by the third and fourth exons; the three LIM domains are encoded by the 13th to 18th exons. The red line indicates the probe used RPA spanning coding sequences from exon 7 to 12. (B) Schematic representation of the exonic organization of the four known enh splice variants. The red lines indicate the length of the RPA probe protected from RNase digestion by hybridization to the various ENH isoforms.