. Author manuscript; available in PMC: 2010 May 12.

Published in final edited form as: Pediatr Infect Dis J. 2010 May;29(5):391–396. doi: 10.1097/INF.0b013e3181c38f3b

TABLE 2.

Response Rates and rSBA Titers by Serogroup

Serogroup	Geometric Mean Titer (95% Confidence Limits)		Median (Interquartile Range^*) Titer		≥4-Fold Increase in rSBA Titer at Week 4	rSBA Titer ≥128
Serogroup	Week 0	Week 4	Week 0	Week 4	≥4-Fold Increase in rSBA Titer at Week 4	Baseline	Week 4
A	39 (28, 53)	1424 (1039, 1951)	<8 (<8, 512)	2048 (512, 8192)	68%	41%	86%
C	8 (6, 9)	107 (75, 154)	<8 (<8, <8)	256 (<8, 2048)	52%	11%	55%
W-135	9 (8, 11)	239 (179, 318)	<8 (<8, <8)	512 (64, 2048)	73%	15%	72%
Y	28 (22, 36)	303 (227, 403)	<8 (<8, 128)	512 (64, (2048)	63%	35%	73%

Due to assay limitations, exact titers could not be provided for results <8 or >131,072. For purposes of calculating medians and geometric mean titers, results <8 were set equal to 4 and those > 131,072 were set equal to 262,144. Interquartile range: 25th percentile to 75th percentile.