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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Semin Cutan Med Surg. 2010 Mar;29(1):3–9. doi: 10.1016/j.sder.2010.03.001

Figure 3. Model of Th1-Th2-Th17 interactions.

Figure 3

Effector T cells subsets stimulated by antigen-presenting cells (APC) in psoriasis include Th1 and Th17 cells. Th2 cells and associated cytokines, IL-4 and IL-13, that can suppress Th1 and Th17 activity, are decreased in psoriasis. Genes that confer risk of having psoriasis include IL4 and IL13 (box).