Table 2.
Qualitative Grading of UBM Images in Cases and Controls (All Quadrants, Right Eyes)
| Number of Eyes (proportion) | Superior |
Nasal |
Inferior |
Temporal |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Control-1 | Control-2 | P* | Cases | Control-1 | Control-2 | P* | Cases | Control-1 | Control-2 | P* | Cases | Control-1 | Control-2 | P* | |
| Iris thickness, basal | ||||||||||||||||
| Thin | 29 (24.79) | 21 (36.21) | 17 (35.42) | 27 (23.08) | 19 (32.76) | 16 (33.33) | 32 (27.35) | 26 (44.83) | 21 (43.75) | 43 (36.75) | 23 (39.66) | 18 (37.50) | ||||
| Medium | 69 (58.97) | 20 (34.48) | 16 (33.33) | P1 = 0.008 | 54 (46.15) | 22 (37.93) | 18 (37.50) | P1 = 0.365 | 49 (41.88) | 18 (31.03) | 14 (29.17) | P1 = 0.068 | 51 (43.59) | 24 (41.38) | 21 (43.75) | P1 = 0.932 |
| Thick | 19 (16.24) | 17 (29.31) | 15 (31.25) | P2 = 0.009 | 36 (30.77) | 17 (29.31) | 14 (29.17) | P2 = 0.370 | 36 (30.77) | 14 (24.14) | 13 (27.08) | P2 = 0.108 | 23 (19.66) | 11 (18.97) | 9 (18.75) | P2 = 0.990 |
| Iris thickness, overall | ||||||||||||||||
| Thin | 5 (4.27) | 3 (5.17) | 3 (6.25) | 7 (5.98) | 3 (5.17) | 3 (6.25) | 14 (11.97) | 10 (17.24) | 9 (18.75) | 20 (17.09) | 13 (22.41) | 11 (22.92) | ||||
| Medium | 76 (64.96) | 34 (58.62) | 28 (58.33) | P1 = 0.716 | 63 (53.85) | 36 (62.07) | 30 (62.50) | P1 = 0.677 | 68 (58.12) | 34 (58.62) | 27 (56.25) | P1 = 0.535 | 74 (63.25) | 33 (56.90) | 26 (54.17) | P1 = 0.651 |
| Thick | 36 (30.77) | 21 (36.21) | 17 (35.42) | P2 = 0.691 | 47 (40.17) | 19 (32.76) | 15 (31.25) | P2 = 0.645 | 35 (29.91) | 14 (24.14) | 12 (25.00) | P2 = 0.488 | 23 (19.66) | 12 (20.69) | 11 (22.92) | P2 = 0.535 |
| Iris convexity | ||||||||||||||||
| Absent | 3 (2.56) | 5 (8.62) | 5 (10.42) | 2 (1.71) | 6 (10.34) | 6 (12.50) | 2 (1.71) | 4 (6.90) | 4 (8.33) | 4 (3.42) | 9 (15.52) | 9 (18.75) | ||||
| Mild | 96 (82.05) | 43 (74.14) | 34 (70.83) | 95 (81.20) | 37 (63.79) | 31 (64.58) | 92 (78.63) | 44 (75.86) | 37 (77.08) | 94 (80.34) | 46 (79.31) | 38 (79.17) | ||||
| Moderate | 18 (15.38) | 10 (17.24) | 9 (18.75) | P1 = 0.174 | 18 (15.38) | 15 (25.86) | 11 (22.92) | P1 = 0.011 | 21 (17.95) | 10 (17.24) | 7 (14.58) | P1 = 0.253 | 18 (15.38) | 3 (5.17) | 1 (2.08) | P1 = 0.009 |
| Extreme | 0 (0.00) | 0 (0.00) | 0 (0.00) | P2 = 0.078 | 2 (1.71) | 0 (0.00) | 0 (0.00) | P2 = 0.010 | 2 (1.71) | 0 (0.00) | 0 (0.00) | P2 = 0.160 | 1 (0.85) | 0 (0.00) | 0 (0.00) | P2 = 0.001 |
| Iris insertion | ||||||||||||||||
| Basal | 75 (64.10) | 38 (65.52) | 32 (66.67) | 61 (52.14) | 27 (46.55) | 24 (50.00) | 72 (61.54) | 36 (62.07) | 32 (66.67) | 48 (41.03) | 25 (43.10) | 23 (47.92) | ||||
| Middle | 39 (33.33) | 19 (32.76) | 16 (33.33) | P1 = 0.934 | 51 (43.59) | 29 (50.00) | 23 (47.92) | P1 = 0.721 | 45 (38.46) | 21 (36.21) | 16 (33.33) | P1 = 0.355 | 66 (56.41) | 32 (55.17) | 25 (52.08) | P1 = 0.918 |
| Apical | 3 (2.56) | 1 (1.72) | 0 (0.00) | P2 = 0.531 | 5 (4.27) | 2 (3.45) | 1 (2.08) | P2 = 0.733 | 0 (0.00) | 1 (1.72) | 0 (0.00) | P2 = 0.535 | 3 (2.56) | 1 (1.72) | 0 (0.00) | P2 = 0.423 |
| Iris angulation | ||||||||||||||||
| None | 84 (71.79) | 39 (67.24) | 33 (68.75) | 84 (71.79) | 43 (74.14) | 33 (68.75) | 76 (64.96) | 38 (65.52) | 32 (66.67) | 65 (55.56) | 42 (72.41) | 35 (72.92) | ||||
| Mild | 24 (20.51) | 13 (22.41) | 11 (22.92) | P1 = 0.779 | 23 (19.66) | 12 (20.69) | 12 (25.00) | P1 = 0.725 | 29 (24.79) | 16 (27.59) | 13 (27.08) | P1 = 0.741 | 32 (27.35) | 10 (17.24) | 8 (16.67) | P1 = 0.098 |
| Pronounced | 9 (7.69) | 6 (10.34) | 4 (8.33) | P2 = 0.925 | 10 (8.55) | 3 (5.17) | 3 (6.25) | P2 = 0.694 | 12 (10.26) | 4 (6.90) | 3 (6.25) | P2 = 0.709 | 20 (17.09) | 6 (10.34) | 5 (10.42) | P2 = 0.117 |
| Ciliary body size | ||||||||||||||||
| Small | 41 (35.04) | 17 (29.31) | 10 (20.83) | 37 (31.62) | 21 (36.21) | 12 (25.00) | 31 (26.50) | 18 (31.03) | 13 (27.08) | 17 (14.53) | 5 (8.62) | 0 (0.00) | ||||
| Medium | 49 (41.88) | 27 (46.55) | 25 (52.08) | P1 = 0.742 | 61 (52.14) | 28 (48.28) | 28 (58.33) | P1 = 0.830 | 52 (44.44) | 24 (41.38) | 21 (43.75) | P1 = 0.819 | 56 (47.86) | 26 (44.83) | 23 (47.92) | P1 = 0.383 |
| Large | 27 (23.08) | 14 (24.14) | 13 (27.08) | P2 = 0.198 | 19 (16.24) | 9 (15.52) | 8 (16.67) | P2 = 0.688 | 34 (29.06) | 16 (27.59) | 14 (29.17) | P2 = 0.996 | 44 (37.61) | 27 (46.55) | 25 (52.08) | P2 = 0.013 |
| Ciliary body rotation | ||||||||||||||||
| Neutral | 46 (39.32) | 21 (36.21) | 19 (39.58) | P1 = 0.690 | 31 (26.50) | 20 (34.48) | 19 (39.58) | P1 = 0.274 | 69 (58.97) | 27 (46.55) | 25 (52.08) | P1 = 0.120 | 51 (43.59) | 30 (51.72) | 28 (58.33) | P1 = 0.310 |
| Anterior | 71 (60.68) | 37 (63.79) | 29 (60.42) | P2 = 0.975 | 86 (73.50) | 38 (65.52) | 29 (60.42) | P2 = 0.097 | 48 (41.03) | 31 (53.45) | 23 (47.92) | P2 = 0.417 | 66 (56.41) | 28 (48.28) | 20 (41.67) | P2 = 0.085 |
Data are presented as counts (proportions) by column. The grading is based on standard photographs of all quadrants in the right eyes.
*
The P-values of Pearson χ2 test for the comparison of proportions of UBM features in cases and controls. P1 is for comparison between cases and the controls defined by pigment trabecular meshwork not visible in less than two quadrants (control-1); P2 was for comparison between cases and the controls defined by PTM visible in all quadrants (control-2).