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. 2010 Mar;51(3):1517–1523. doi: 10.1167/iovs.09-4348

Figure 2.

Figure 2.

Invasion of A. nidulans strains in porcine corneal tissue at pH 7.3 on day 3 after scarification and topical inoculation. (A) Wild-type strain A83 proliferated on the corneal surface and formed hyphae that branched into the anterior stroma. (B) Noninfected control cornea. (C) Strain B7, lacking PalB protease, produced scant hyphae in the superficial cornea. (D) Rescuant strain B7R was similar to wild-type, with extensive fungal invasion throughout the anterior cornea. (E) Strain C6309, lacking the PacC transcription factor, produced no hyphae, and corneal epithelium remained intact. (F) Rescuant strain C6309R produced hyphae that invaded the anterior third of the cornea. PAS staining. Scale bar, 50 μm. Magnification, ×200.