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. 2010 Feb;51(2):816–821. doi: 10.1167/iovs.09-3952

Figure 5.

Figure 5.

Mature dendritic cells facilitate Treg suppressor function. (A) Mature or immature BMDCs were cocultured with allogeneic CD4+CD25 Teff and CD4+CD25+ Treg from naive mice. Total cell number of DC/Treg/Teff is 1:5:10. Treg suppression potency was compared between mature and immature BMDC groups. (B) Treg suppressor potential was also tested at different mature BMDC/Treg cell number ratios. Total cell number of Treg/Teff is 1:2. The x-axis shows the different ratios of mature BMDC/Treg. Results are depicted as the percentage of suppression (mean ± SEM) and represent the results of 1 of 3 independent experiments (*P < 0.05).