Table 2.

General Characteristics of the Y402H Studies Selected

Study	Year	Country	Ethnicity	Sample Size*	Mean Age	Disease† and Study
Baird et al.38	2006	Australia	European	144	70	AMD-MVIP
Brantley et al.39	2007	Unites States	European	189	69.5	AMD-AREDS
Chen et al.40	2006	China	Chinese	244	73.5	AMD
Chowers et al.41	2008	Israel	Israeli	1180	70.8	AMD
Conley et al.42	2005	Unites States	European	210		AMD
DeJong et al.43	2007	Netherlands	European	5066		AMD-Rotterdam
Despriet et al.44	2006	Netherlands	European	3619		AMD
				2392
Droz et al.45	2008	Switzerland	European	52	74.9	AMD
Edwards et al.46	2005	Unites States	European	134		AMD
			European	68		AMD
Fisher et al.47	2007	Russia	European	151	71	AMD
Fuse et al.48	2006	Japan	Japanese	192	68.6	AMD
Gotoh et al.49	2006	Japan	Japanese	105	60.2	AMD
Gotting et al.50	2008	German	European	189	0	AMD
Grassi et al.8	2006	Unites States	African	75		AMD
			European	148
			Hispanic	81
			Japanese	82
			Somali-African	128
Hageman et al.18	2005	Unites States	European	131	78.4	AMD
			European	275	68.84
Haines et al.51	2005	Unites States	European	24	69.8	AMD
Jakobsdottir et al.52	2005	Unites States	European	117		AMD
Kaur et al.19	2006	India	Indian	120	63.9	AMD
Kim et al.53	2008	Korea	Koreans	187		AMD
Lau et al.54	2006	China	Chinese	232		AMD
Lee et al.55	2008	Singapore	Chinese	93		AMD
LeFur et al.56	2008	France	European	6348		Dementia
			European	642		Alzheimer's
Lin et al.57	2008	Taiwan	Chinese	180		AMD
Magnusson et al.58	2006	Iceland	Icelandic	171		AMD
			Icelandic	891		AMD
		Unites States	European	203		AMD
Maller et al.59	2006	Unites States	European	934	74	AMD-AREDS
Mooijaart et al.60	2007	Netherlands	European	640		Inflammation,
			European	552		Cardiovascular-PAMD
Mori et al.61	2007	Japan	Japanese	139		AMD
Narayanan et al.62	2006	Unites States	European	58	72.5	AMD
Ng et al.63	2008	China	Chinese	155	73.1	AMD
Okamoto et al.64	2006	Japan	Japanese	89		AMD
Pai et al.65	2007	Unites States	European	499	65.1	Coronary
			European	473	60.3	Heart Disease
Pulido et al.66	2007	Unites States	European	120		Coronary Heart Disease
Rivera et al.67	2005	Germany	European	611		AMD
			European	335
Schaumberg et al.68	2007	Unites States	European	1071	60.2	AMD-NHS
Seddon et al.16	2006	Unites States	European	280		AMD
Seitsonen et al.69	2006	Finland	European	105	76.9	AMD
Sepp et al.70	2006	England	European	262	75.8	AMD
Simonelli et al.71	2001	Italy	European	47	0	AMD
Souied et al.72	2005	France	European	91	74.6	AMD
Stark et al.73	2007	Germany	European		56.9	Myocardial Infarction-GMI
				973
Tanimoto et al.74	2007	Japan	Japanese	99	73.5	AMD
Tedeschi-Blok et al.75	2007	Unites States	Hispanic	570		AMD-LALES
Uka et al.76	2006	Japan	Japanese	107		AMD
Volcick et al.77	2008	Unites States	African	3010		Atherosclerosis-ARIC
			European	8217
Wegscheider et al.78	2007	Austria	European	163	77.5	AMD
Xing et al.79	2008	Australia	European	2381		AMD-Blue Mountains
Xu et al.80	2008	China	Chinese	132	66.1	AMD
Zareparsi et al.81	2005	Unites States	European	275		AMD
Zee et al.82	2006	Unites States	European	335		Cardiovascular diseases-PHS
			European	235
			European	34
Zetterberg et al.83	2008	Sweden	European	1265	78.6	Alzheimer's
Ziskind et al.13	2008	South Africa	African	98	76	AMD

LALES, Los Angeles Latino Eye Study; MVIP, Melbourne Visual Impairment Project; NHS, Nurses' Health study; BMI, German Myocardial Infarction Study; PHS, Physician Health Study; ARIC, Atherosclerosis Risk in Communities.

^*Sample sizes of the control group.

^†Disease studied.