Table 1.
Clinical and radiologic characteristics
| Patient | Sex | Age at surgery years | Age at puberty years | Type | Attachment to tuber cinereum/infundibulum | Maximal diameter mm | Area of attachment base, mm2 | Volume cm3 | Site of attachment |
|---|---|---|---|---|---|---|---|---|---|
| CPP | |||||||||
| 2092 | M | 1.1 | 0.8 | 3 | + | 18.0 | 1.30 | 4.49 | L |
| 2027 | M | 2.5 | 2.0 | 3 | + | 16.6 | 0.95 | 3.91 | B |
| 2017 | M | 4.8 | 3.2 | 1 | + | 13.8 | 0.27 | 2.46 | R |
| 2021 | M | 11.3 | 1.0 | 2 | + | 14.9 | 1.36 | 2.56 | B |
| 2008 | M | 13.8 | 6.5 | 4 | + | 30.6 | 1.84 | 15.70 | B |
| 2079 | F | 11.6 | 0.6 | 4 | + | 30.9 | 2.28 | 28.28 | B |
| 2062 | F | 19.3 | 6.0 | 4 | + | 23.9 | 0.84 | 11.19 | B |
| No CPP | |||||||||
| 2094 | M | 9.5 | N/A | 2 | − | 8.4 | 0.30 | 0.38 | L |
| 2077 | M | 11.2 | 13a | 2 | − | 7.7 | 0.48 | 0.38 | R |
| 2088 | M | 12.8 | 12a | 2 | − | 7.4 | 0.36 | 0.31 | L |
| 2065 | M | 13.3 | N/A | 2 | − | 13.8 | 1.03 | 1.75 | R |
| 2081 | M | 13.8 | 15a | 2 | − | 14.4 | 1.15 | 1.70 | L |
| 2051 | F | 9.2 | 9b | 2 | − | 9.5 | 0.54 | 0.56 | R |
| 2050 | F | 10.5 | 12c | 2 | − | 9.1 | 0.46 | 0.45 | L |
| 2080 | F | 11.8 | N/A | 1 | + | 19.6 | 1.40 | 5.00 | L |
| 2015 | F | 13.3 | N/A | 1 | − | 9.5 | 0.17 | 0.64 | R |
| 2025 | F | 17.4 | 12c | 3 | − | 14.1 | 1.20 | 2.02 | R |
| 2013 | F | 19.5 | 14c | 4 | + | 25.4 | 1.04 | 8.15 | B |
CPP = Central precocious puberty; N/A = not available; L = left; R = right; B = bilateral. Hamartoma type is according to the classification of Delalande and Fohlen [21]: type 1, subhypothalamic; type 2, intraventricular; type 3, both subhypothalamic and intraventricular; type 4, ‘giant’ hamartoma, here defined as volume >8 cm3.
a
Voice change.
b
Breast development.
c
Menarche.