Table 2.
Receiver operating characteristics analysis of echocardiographic parameters to predict pulmonary capillary wedge pressure ≥18 mmHg
| Cutoff value | Sensitivity (95% CI)(%) |
Specificity (95% CI)(%) |
AUC | |
|---|---|---|---|---|
| Two-dimensional Echo | ||||
| LV EDV | >278 ml | 50.0 (15.6-85.6) | 88.2 (46.3-99.6) | 0.60 |
| LA area | >36.5 cm2 | 60.0 (32.4-84.1) | 50.0 (16.1-85.3) | 0.68 |
| LA volume indexed | >37.8 ml/m2 | 67.9 (53.9-96.8) | 87.5 (56.9-95.7) | 0.78 |
| Mitral flow Doppler | ||||
| Mitral E wave | > 94.2 cm/s | 90.1 (66.8-99.7) | 66.8 (26.3-93.2) | 0.72 |
| E/A ratio | >2.6 | 89.4 (65.1-97.2) | 65.2 (24.3-92.9) | 0.70 |
| Tissue Doppler | ||||
| Mean E/Em ratio | >16.8 | 67.9 (27.8-91.5) | 93.1 (76.9-99.8) | 0.69 |
| Speckle tracking | ||||
| Global PALS | <15.1% | 100 (83.9-100) | 93.2 (78.1-99.8) | 0.93 |
(AUC, Area under the curve; CI, confidence interval; LV, left ventricular; EDV, end diastolic volume; LA, left atrial; E, early transmitral flow velocity; A. atrial transmitral flow velocity; Em, early diastolic mitral annular velocity; PALS, peak atrial longitudinal strain).