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. Author manuscript; available in PMC: 2010 May 12.
Published in final edited form as: N Engl J Med. 2009 May 7;360(19):1929–1931. doi: 10.1056/NEJMp0902195

The Three Translations Required to Improve the Quality of Program Precutaneous Coronary Intervention (PCI) in Patients with Acute Myocardial Infraction.

Translational Tier Type of Research Products of Research
T1 Clinical efficacy research Proof that primary PCI is more effective than fibrinolytic therapy in controlled clinical trials
T2 Comparative-effectiveness and health services research Establishment of a 90-minute standard for the interval between arrival in the emergency department and the initiation of coronary intervention
T3 Implementation research Identification of hospital-based strategies to reduce the time to PCI and establishment of consortium to guide local integration of strategies