Table 4.
Genes common to significance and SVM analyses
SVM Gene | log2(Fold Change) | Description (if available) | 8 hrs | 24 hrs |
---|---|---|---|---|
CYR61 | -1.51 | cysteine-rich, angiogenic inducer, 61 | + | + |
SOCS3 | -1.06 | suppressor of cytokine signaling 3 | - | + |
AK024238 | -1.32 | mRNA, possibly cadherin 6, type 2 (CDH6) | + | + |
AA768672 | -1.47 | mRNA, possibly LSM14A | + | + |
THC2348879 | -1.22 | + | - | |
THC2313287 | -2.74 | + | + | |
IER2 | -1.64 | immediate early response 2 | + | + |
ZFP36 | -1.74 | zinc finger protein 36 | + | + |
FOS | -3.47 | v-fos FBJ murine osteosarcoma viral oncogene homolog | + | + |
NFKBIE | 1.08 | nuclear factor of kapppa light polypeptide gene enhancer in B-cells inhibitor | + | + |
AT_nC_3 | -1.32 | + | - | |
CTGF | -1.43 | connective tissue growth factor | + | - |
AF159295 | -1.89 | mRNA, MAP/microtubule affinity-regulating kinase 3 (MARK3) | + | + |
JUN | -1.74 | v-jun sarcoma virus 17 oncogene homolog (avian) | + | + |
FOSB | -2.18 | FBJ murien osteosarcoma viral oncogene homolog B | + | + |
EGR1 | -3.18 | early growth response 1 | + | + |
HP1BP3 | -1.00 | heterochromatin protein 1, binding protein 3 | + | - |
DUSP1 | -1.79 | dual specificity phosphatase 1 | + | + |
ABCC3 | 1.38 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | + | + |
FOXC1 | -1.15 | forkhead box C1 | - | + |
SFRS5 | -1.47 | splicing factor, arginine/serine-rich 5 | + | + |
DB363693 | -1.43 | + | - | |
THC2343678 | -1.47 | + | + | |
A_24_P161068 | -1.09 | - | + |
Genes are listed in order of importance in the SVM analysis. The fold change in each gene is the average fold change in gene expression including both the 8 and 24 hour data. In the last two columns, a "+" indicates that the gene was found in both the Significance and SVM Analyses at 8 or 24 hours, respectively. A "-" indicates that the gene was not found in the results in both analyses at 8 or 24 hours. Genes through sfrs5 are among the top 35 and through the end of the list are in the top 43.